Comparative susceptibility of chimpanzees and Macaca mulatta monkeys to oral administration of partially purified staphylococcal enterotoxin.

نویسنده

  • B J WILSON
چکیده

Although several species of animals have been reported to be susceptible to staphylococcal enterotoxin, Dack (1956) stated ". . . no experimental animal has been found that will react to the small amount of enterotoxin sufficient to cause severe reactions in man." Of the few animals regularly used to determine the presence of toxin in test samples of material, the Macaca mulatta monkey fed by stomach tube probably gives the most reliable results, since elaborate controls to eliminate nonspecific reactions sometimes noted in parenteral administration of samples to cats, pigs, and other animals are not required (Surgalla et al., 1953). A direct comparison in susceptibility of Macaca mulatta and man to enterotoxin has not been reported, but rough estimates indicate that man is many times more reactive than the monkey (Dack, 1956). This paper presents data on the reaction of a small group of chimpanzees to staphylococcal enterotoxin which indicate that this species is one of the most susceptible experimental animals available.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Effect of formaldehyde on the immunogenicity of staphylococcal enterotoxin B for Macaca mulatta.

Monkeys were immunized with enterotoxin and enterotoxoid by intracutaneous injection or by feeding. Identical schedules were used to compare the effectiveness of the two antigens and the two routes. Enterotoxin administered intracutaneously was the most effective antigen, whereas oral administration of enterotoxoid was least effective. Intracutaneous injection of toxoid and oral feeding of toxi...

متن کامل

Recognizing facial cues: individual discrimination by chimpanzees (Pan troglodytes) and rhesus monkeys (Macaca mulatta).

Faces are one of the most salient classes of stimuli involved in social communication. Three experiments compared face-recognition abilities in chimpanzees (Pan troglodytes) and rhesus monkeys (Macaca mulatta). In the face-matching task, the chimpanzees matched identical photographs of conspecifics' faces on Trial 1, and the rhesus monkeys did the same after 4 generalization trials. In the indi...

متن کامل

The composite face effect in chimpanzees (Pan troglodytes) and rhesus monkeys (Macaca mulatta).

The accurate recognition of individuals is a cornerstone of social exchange in primates. Current approaches to the study of individual recognition, however, are focused on human performance and only occasionally reference comparative research for support. A number of studies have suggested that humans can easily recognize thousands of individual faces and that this perceptual expertise is suppo...

متن کامل

Pathogenesis of lethal shock after intravenous staphylococcal enterotoxin B in monkeys.

The pathogenesis of shock in the rhesus monkey given intravenous staphylococcal enterotoxin B (SEB) is not understood. Several cardiovascular changes produced by a highly purified preparation of SEB were studied after administration of doses ranging from 50 to 1,000 mug/kg. Irreversible arterial hypotension was found consistently at the higher doses. Arterial blood pressure and cardiac output d...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:
  • Journal of bacteriology

دوره 78  شماره 

صفحات  -

تاریخ انتشار 1959